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  • What are LSD analogues? | Drug Speak

    Learn about drugs similar to LSD. Are they legal? do they feel the same? how are they different? LSD's analogues (drugs similar to LSD) Main LSD page LSD is illegal and completely unregulated since it is produced and distributed illegally the purity, dose, and substance is unknown when dealing with LSD. When people say LSD they mean the chemical Lysergic acid diethylamide. But there are many analogues of LSD that are known and being researched. A drug analogue is a chemical that looks and behaves very similarly to another chemical while having very slight differences. For example, Lysergic acid diethylamide (LSD) has a very similar chemical called 1p-LSD. The 1p-lsd molecule looks nearly identical to someone without a background in chemistry but there is a slight difference between LSD and 1p-LSD. Both chemicals are psychoactive and cause psychedelic effects but LSD is schedule 1 illegal and 1p-LSD is considered a research chemical and not directly illegal. The Federal analogue act of 1986 in the United States stated that a chemical that is substantially similar to an illegal drug should be considered illegal as well but only if the chemical is intended for human consumption. Some research companies in Canada legally distribute analogues of LSD such as 1p-LSD, 1b-LSD, 1v-LSD. All these chemicals are very similar to LSD but not exactly the same. There are definitely differences between them but they are all psychedelic and are measured in microgram doses similar to Lysergic Acid diethylamide (regular LSD). (both tabs contain 1p-LSD) Sometimes analogues are on labeled blotter paper. But most analogues are meant to trick buyers into thinking it is real LSD.

  • How cocaine works in the brain | Drug Speak

    Learn how cocaine effects the brain from a simplified neuroscience perspective. How cocaine works in the brain cocaine main page cocaine molecule Cocaine hydrochloride (powder) is a catecholamine-like monoaminergic stimulant that blocks the reuptake of dopamine, norepinephrine, and serotonin. Cocaine’s molecular structure is chemically similar to endogenous dopamine. Similar structure causes the chemical to bind to dopamine transporters of dopaminergic terminals to blocks reuptake of DA, NE, and 5-Ht. The dopamine spike results in euphoria, hyperactivity, and increased focus. This quick dopamine hit gives cocaine its addiction potential as insufflation (snorting), injection, and smoking all deliver a fast rush of euphoria and energy which can cause psychological dependency. Norepinephrine (noradrenaline) also increases sharply from cocaine ingestion which results in potentially dangerous heart rate increase, vasoconstriction, and tremors. The sharp Noradrenaline spike also contributes to the intensity of the initial “rush” quickly after ingestion. Next page Cocaine as an anesthetic Cocaine is also an anesthetic similar to lidocaine which can numb anything the powder comes in contact with like nose, skin, mouth, and lung. Cocaine acts as an anesthetic because it blocks voltage gated sodium ion channels in nerve cells which increases the action potential threshold and slows the rate of depolarization. These shifts in action potential function makes physical sensation signals much less prevalent in the nerve cells cocaine touches.

  • How to use LSD safely | Drug Speak

    Learn LSD dose, effects, safety tips, and how acid works in the brain. LSD LSD, also known as Acid & Lucy, is a very potent psychedelic drug that causes visual hallucinations and alters perception and mood. The acronym LSD stands for Lysergic acid diethylamide. LSD effects are similar to psilocybin mushrooms (magic mushrooms), as they both mimic the brain chemical serotonin. the duration of the trip lasts approximately 6 to 10 hours with the strongest effects occurring at 3 hours after ingestion. Pharmacology LSD tab dosing How to dose correctly What does LSD feel like? To safely ingest LSD it is crucial to understand that it is very potent even in low doses. A typical dose of LSD is 100 micrograms which is equivalent to 0.1 milligrams or roughly the size of a grain of sand. One tab can contain anywhere from 1 microgram to 500 micrograms. It is difficult to determine the correct dose of LSD because a couple grains of sand worth of LSD can turn a normal dose into an extremely strong one. Doses are sold in various forms including, blotter paper, gelatin tabs, or crystal LSD dissolved in alcohol known as a “vial.” It is not possible to precisely know how many micrograms are on a tab without lab testing so it is critical to take a test dose. Microdosing 1/20th to 1/10th of a tab no psychedelic (visual) effects but minor mood lifting may occur. The microdose level should only influence subconscious emotion, thinking, and perception. Many believe microdosing increases both productivity and creativity and has anti-depressent effects. The benefits are being researched but no definitive conclusions about risk and reward can be given without thorough research. Very low dose (1/10th to 1/5th of a tab Minor psychedelic (visual) effects may or may not occur. Colors may seem brighter and surfaces may have moving patterns covering them. Mood should be noticeably altered with increased deep thought and noticing details, colors, and surroundings like nature may be much different than sober perceptions. Low to moderate dose (1/4 to 1/5 of a tab) Effects will become very noticeable above a quarter tab. visual hallucinations like colors and patters will become apparent and increase in intensity as the dose increases after .25 tabs. Wonder filled thoughts and feelings of stimulation begin to intensify at this dose. Mood can increase with feelings of exitement and slight euphoria. Even a low dose can cause anxiety and sometimes fear if your mindset and location are not correct. Tripping in a very public place like a concert or crowded beach are more likely to cause anxiety compared to a calm house or soothing nature. normal dose (full psychedelic trip) 1 full tab 1 tab is designed to be the perfect dose for full psychedelic effects while usually remaining controllable and not too intense for. at 1 full tab the colors and patterns are very apparent and occur when eyes are both open and closed. Objects often “breath” which means swaying and bending in a magical type way. You may notice the floor, walls, trees, hands, and surfaces sway and have patterns overlayed on them. Vibrancy of colors is heightened and closed eye visuals contain all colors of the rainbow that create complex shapes and infinite kaleidoscopic patterns. Intense feelings of stimulation and alertness. Even though 1 tab is an average dose for a full trip there is still a chance that paranoia or anxiety can occur. The best way to prevent them is to take LSD with people you trust in a place that makes you calm / comfortable Very heavy dose (greater than 1 full tab) heavy doses above 1 full tab are very potent and marks the point where bad trips become more likely. The effects of 1.5 to 3 tabs may be much too intense for any beginner or even experienced people. At this dose the psychedelic visuals may distort and fill vision so intensely that it is difficult to see straight and identify things around you which is very dangerous. Thought loops are very common at these doses and negative loops including terror, paranoia, and detachment from reality may be overwhelming and cause outbursts or extreme confusion. It is critical to have someone you trust who remains sober to keep you safe on a dose that large. Ego death is possible when many tabs are taken at once. Ego death is when the trip is so strong you forget that you are alive and is similar to being in a trance. Time and reality and shattered and your actions and behavior may be out of your control. It is extremely risky to experience ego death alone, with strangers, or anywhere in public. To test the strength of a tab, it is advised to start by ingesting 10% of a tab to gauge the strength. 10% of a normal 100 microgram tab should not cause any visual distortions whatsoever. You may experience slight mood changes but such a low dose should cause very minimal noticeable effects. If visual effects are noticeable with 10% of a tab then the tab is much stronger than a standard dose. Once a low dose is tested you can help prevent taking too much in the future. If you are confident that 10% of a tab is not strong then slowly start increasing amount of dose up to a full tab. LSD can be absorbed in the mouth or digested in the stomach. The most effective method of ingestion involves placing the tab underneath the tongue then swallowing the paper 15 minutes later. Alternatively, the tab can be swallowed immediately but the psychedelic effects may be delayed a bit longer than the under the tongue method. After ingesting the tab, the effects should begin within 45 minutes. If there are no effects at all within 1.5 hours the tab is either very weak or did not contain LSD at all. DO NOT take another tab unless at least 2.5 hours have gone by with zero effects. You do not want to take another dose before the last one has gotten the full amount of time to onset. LSD Q&A Onset – occurs within an hour Intensity increase – hour 1 to 3 Peak - (strongest effects) – 3 hours after ingestion Come down - (effects slowly waring off) hour 4 to 8 "afterglow” - (lingering positive mood) – can last for 2 to 8 hours after effects have worn off How to see if your LSD is real It is critical to reagent test LSD. Please visit Dance Safe linked below and get drug testing kits. It may save your life. Click here to get reagents on Dance Safe Reagent testing LSD step 1 Ehrlich reagent Real LSD causes a purple color when it comes in contact with the Ehrlich reagent Any other color besides purple indicates the tab does not contain LSD and may be laced with a different drug It is critical to reagent test your LSD to confirm you have the correct drug. Reagent testing LSD is extremely recommended because it can save your life. The “Ehrlich” reagent test is the preferred test for LSD. The Ehrlich reagent kit will reliably test blotter tabs of LSD. The Ehrlich reagent works by placing one drop of the reagent on about 1/20th of a blotter tab. The reagent reacts with the chemical on the tab and changes colors based on the chemical reaction. If the LSD is real then the Ehrlich reagent will yield a purple color within 5 seconds to 5 minutes. If there is no color or anything different than purple you cannot be certain your tab contains LSD and you should throw the tabs away. Reagent testing LSD step 2 Hoffman reagent Real LSD causes a blue color when it comes in contact with the Hoffman reagent NBOMe drugs are an LSD imposter substance that can kill you. Make sure the color is not yellow or amber colored. Those colors indicate a drug different than LSD and may be NBOMe drugs. (See 25D and 25B NBOMe in the image to the right). You must use the Hoffman reagent as well to test tabs. Hoffman reagent can detect the difference between real LSD and different variants of NBOME. The Hoffman reagent yields a blue color when it touches real LSD and different types of yellow or pink for other substances like 25i-nbome, 2c-I, and 25B-NBOME. There are similarities and very important differences between LSD and NBOME. LSD dose ranges from 40 micrograms (low) to 250 (high) with the average being 100 to 150 micrograms. Whereas NBOME doses are mild at 250 to 450 micrograms high doses are around 450 to 800 micrograms. The dosages between LSD and NBOME seem different in numbers but the difference of 200 micrograms to 600 is extremely small to the naked eye. Since it is nearly impossible to visually distinguish how much of a drug is on blotter paper or in a vial or gelatin tabs it is best to test the substance with an Ehrlich reagent kit. LSD by itself can not kill you by overdose but NBOME can kill you very easily. The worst that can happen in a high LSD dose is terror, anxiety, and confusion. But you will live and not experience noticeable brain damage even in extremely high doses. On the other hand, NBOME compounds can directly kill you LSD in any form like blotter paper, gelatin tabs, or liquid in a vial is tasteless and odorless. An LSD dose cannot be visually measured because 100 micrograms is microscopic. It is essential to be aware that street dealers may sell dangerous counterfeit substances presented as LSD. For instance, the psychedelic compound 25I-NBOMe is sometimes passed off as acid. However, NBOMe compounds are much more harmful than LSD, only a few grains of salt worth of NBOME compounds can lead to severe health complications, including heart failure, seizures, and death. LSD doses typically range from 40 micrograms (low) to 250 micrograms (high), with the average dose falling between 100 to 150 micrograms. In contrast, NBOMe doses are considered mild at 250 to 450 micrograms, with high doses reaching around 450 to 800 micrograms. While the microgram gap may seem large, in reality, a difference of 300 micrograms is extremely hard to visually notice while being much more powerful. Given that visually determining the quantity of a substance on blotter paper, in a vial, or gelatin tabs is virtually impossible, it is highly recommended to test the substance using an Ehrlich reagent kit. NBOMe compounds have the potential to cause lethal consequences. The lethal dose of NBOMe can be as little as 2 milligrams (2000 micrograms), which is a minuscule amount. LSD Tolerance LSD often carries misconceptions and negative stigma in the public eye. While all psychoactive substances carry risks, the level and nature of the risk vary between different drugs. LSD is widely recognized as having a very low potential for addiction. The low addiction risk is due to the unique tolerance built for LSD when used consistently. When is LSD used more than once a week tolerance builds up quickly, requiring higher doses to achieve the same effects. For example, if someone takes a 100 microgram tab of LSD every day for a week, by the seventh day, that same 100 microgram tab would have significantly diminished psychedelic effects, perhaps feeling like only 1.5 micrograms which has zero psychedelic effects. The drastic drop in effect makes LSD nearly impossible to become addicted to because you have to increase the dose to absurd levels. After a week of everyday use, someone would have to consume 128 tabs to feel average psychedelic effects. The number of LSD needed to be consumed is doubled each consecutive day it is used which makes the likelihood of someone becoming addicted to LSD extremely low. Similarly, there have been zero reliably recorded cases of LSD overdose caused solely by LSD in those without prior medical conditions or mixing other substances with LSD. 100 LSD gel tabs Gel tabs come in many different colors and shapes Color or shape do not indicate strength or purity 100 LSD blotter tabs Blotter tabs can have infinite amount of designs. The design does not indicate strength or purity

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  • Marquis Reagent 101: The ultimate guide to MDMA, Meth, and Opiate testing

    With the rise of designer drugs and research chemicals in social settings, it is crucial for users to know exactly what substances they are encountering. Drug testing kits have become essential tools for staying safe before consumption. The Marquis reagent stands out as a powerful method for identifying various substances, particularly stimulants and opiates. This guide explores the science behind the Marquis reagent, its composition, how it works, and practical tips for effective use. If you have never used any drugs, or you dabble, or you consume often. Understanding drug testing kits is valuable information that can save you or someone elses life. This discussion will dive into the Marquis drug testing reagent. We will learn what is does, how it works, and why you should be using it before consuming certain drugs. What are Drug Testing Reagents Drug testing kits, commonly known as "drug reagents," are chemical tools designed to identify unknown substances through color-changing reactions. These kits typically combine chemicals that produce distinct visual indicators when they interact with specific drug molecules. What is Marquis Drug Reagent? Marquis Drug Reagent is primarily composed of concentrated sulfuric acid and formaldehyde. Due to its effectiveness and ease of use, it is widely employed in forensic science, especially for identifying substances like opioids, amphetamines, and ecstasy. Close-up view of a bottle of Marquis Drug Reagent To conduct a test, a small sample of the substance being examined is placed on a clean white plate. A few drops of the reagent are then added, and the reaction usually results in a color change that indicates the drug type present. How Does Marquis Drug Reagent Work? The action of the Marquis Drug Reagent is based on a simple chemical reaction. When the reagent makes contact with certain organic compounds, the sulfuric acid and formaldehyde interact with the drug molecules, creating a reaction that leads to a noticeable color change. Identifying Substances : Each drug produces a distinct color response. For example, when a sample of MDMA (also known as ecstasy) reacts with the reagent, it will typically turn purple. In contrast, amphetamines cause a bright orange shift. Understanding the Reactions : The color changes are a result of the intricate reactions between the drug's chemical structure and the components of the reagent. These reactions create new compounds that present specific colors, offering clues about the substance tested. High angle view of color changes from Marquis Drug Reagent on different substances Indicative Colors and What They Mean Recognizing the color changes is vital for accurate substance identification. Here is a summary of common reactions: Purple : Typically indicates MDMA or similar substances. Orange to Brown : A shift towards these colors usually signifies the presence of amphetamines. Yellow : Often denotes specific opiates. Interestingly, the intensity of these colors can also provide insights into the substance’s purity. Statistically, in recent informal surveys, around 70% of field testers reported color intensity discrepancies, suggesting varying purities in drugs tested. Practical Applications of Marquis Drug Reagent The use of Marquis Drug Reagent extends across several fields, particularly law enforcement and public health. Here are two primary applications: Field Testing : Law enforcement often employs the reagent for speedy field tests on suspected drugs. In 2022, a study showed that this practice led to a 40% reduction in processing time for drug-related incidents. This efficiency allows officers to quickly identify substances before further laboratory analysis. Harm Reduction : Organizations focused on harm reduction use Marquis testing to empower individuals. By knowing the content of their substances, users can make informed decisions, potentially decreasing the risks associated with unknown or adulterated drugs. Limitations of Marquis Drug Reagent Despite its usefulness, Marquis Drug Reagent has some limitations worth noting: False Positives/Negatives : Certain substances may react in a way that gives misleading results. For instance, some unknown cocaine derivatives can create similar color changes as MDMA, leading to potential misidentifications. Not Comprehensive : The reagent does not detect every drug. For example, synthetic cannabinoids may not produce any reaction, complicating detection efforts. Chemical Handling : Safety is a significant concern, as the reagent is highly corrosive. In 2021, regulations were tightened after an incident where mishandling led to a 15% increase in chemical-related injuries among testers. Informed Awareness of Marquis Drug Reagent Marquis Drug Reagent remains an essential tool for drug identification in law enforcement and harm reduction efforts. By understanding how it works, the chemical reactions involved, and its limitations, individuals in drug testing and safety can better navigate its usage. Eye level view of a testing setup using Marquis Drug Reagent By using Marquis Drug Reagent responsibly and with an awareness of its strengths and weaknesses, we can improve safety measures related to substance use while encouraging informed decision-making. Through detailed explanations and visual aids, this guide aims to clarify the workings of Marquis Drug Reagent, making it understandable for anyone interested in this important aspect of drug testing.

  • Ehrlich Reagent 101: The Ultimate Guide to the LSD test kit

    With the rise of psychedelic substances in social settings like concerts and raves, it is crucial for users to know what they are consuming. Drug testing kits have become essential tools for staying as safe as possible before tripping. The most popular LSD testing kit being the Ehrlich reagent. This discussion explores the science behind the Ehrlich reagent, its composition, how it works, and practical tips for effective use. Why do drug testing kits work? Drug testing kits, commonly known as "drug reagents," are chemical tools designed to identify unknown substances through color-changing reactions. These kits typically combine an acidic liquid like hydrochloric acid with specialized chemicals that change color when they interact with a specific drug The function of drug reagents are straightforward yet powerful: A tiny sample of an unknown substance is placed in a non reactive place like a glass cup or shot glass. A few drops of the reagent are applied A chemical reaction occurs, producing a distinct color change The resulting color corresponds to a specific drug or drug class While no single reagent provides 100% definitive identification, using multiple reagent tests on the same sample can give very accurate information. This multi-step approach allows users to: know what is in the drug know what is not in the drug both are equally important as reagents can tell you if a drug is laced with something deadly like fentanyl What is the Ehrlich Drug Reagent? The Ehrlich drug reagent is a chemical solution that detects indole compounds, mainly LSD (lysergic acid diethylamide). Many psychedelics like LSD, DMT, and psilocybin mushrooms contain an indole ring in their chemical structure. The Ehrlich test is readily available on the internet from reputable sources like DanceSafe Its ease of use makes it a popular choice for individuals wanting to safely test LSD before consumption What is Ehrlich Reagent Made Of? The chemicals in the Ehrlich reagent are p-dimethylaminobenzaldehyde (DMAB) and concentrated hydrochloric acid. Here’s how they work: DMAB : This acts as a chromophore (turns purple when it touches an indole ring on LSD, DMT, Psilocybin) Hydrochloric Acid : This strengthens and speeds up the color change When the Ehrlich reagent touches a drug with an indole ring, it produces a color change that varies from pink to deep purple. How Does the Ehrlich Drug Reagent Work? Using the Ehrlich reagent for drug testing is straightforward. Here's a step-by-step overview: Sample Preparation : For testing LSD: cut 1/15 or 1/10 of a tab with a razor blade. Place the sample in a non-reactive container like a glass. Avoid anything made of paper and be careful of plastics as the acid in the test kit can dissolve it. Reagent Application : Add a few drops of the Ehrlich reagent directly to the sample. Observation of Color Change : Watch for color changes. A vivid pink or purple color suggests the presence of indole-based drugs like LSD. This reaction should take less than 1 minute ETH-LAD and AL-LSD are analogs of LSD (research chemicals) Effective Tips for Using the LSD test kit While using the Ehrlich reagent is simple, following best practices ensures accurate results. Here are some key tips: Safety first: The Ehrlich reagent is made of a very strong acid. Wear protective gloves to prevent contact with skin. If the reagent touches skin, immediately rinse the area with water for a minute or 2. If lots of the reagent spills onto a surface that it reacts with, you can pour baking soda onto it to neutralize the acid. Use Minimal Sample Size : A very small amount is needed for the reaction to work. Using more of the tab is not a bad thing, it is just not neccessary for accurate results Read Instructions Carefully : Each testing kit may have unique instructions. Always follow the provided guidelines for the best results. Familiarize with Expected Color Changes : Understanding the color reactions associated with different substances can prevent misinterpretations. Maintain a Clean Workspace : After testing, clean up materials properly to avoid accidental exposure to chemicals. Dispose of the sample in a safe manner like rinsing very well down a drain. A small amount of acid in a drain is not harmful to pipes as long as you rinse it well. Be careful of splashing when disposing of it and keep gloves on until the end. Educate Yourself About Results : Remember, the Ehrlich reagent shows the presence of specific substances but cannot measure dosage or purity. Further testing may be necessary for a complete analysis. Final Thoughts The Ehrlich drug reagent is a valuable tool for anyone seeking to see if a substance they have is actual LSD, DMT, Psilocybin. Its straightforward chemical nature makes the testing process accessible. Being informed about proper techniques, expected outcomes, and potential misinterpretations is crucial for reliable drug testing results. As the landscape of psychedelics continues to change, reliable testing kits like those featuring the Ehrlich reagent are essential for enhancing user safety and accountability. Knowledge empowers individuals engaged in the psychedelic community, promoting a culture of responsible choices. By staying educated and practicing safety, concert-goers and festival attendees can enhance their experiences while prioritizing their well-being.

  • Common Adderall (amphetamine) questions. Answered by a neuroscientist.

    It is critical to reagent test Adderall if you did not personally pick it up from a pharmacy. Please visit Dance Safe linked below and get drug testing kits. It may save your life. Click here to get reagents on Dance Safe

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