Learn LSD dose, effects, safety tips, and how acid works in the brain. LSD LSD, also known as Acid & Lucy, is a very potent psychedelic drug that causes visual hallucinations and alters perception and mood. The acronym LSD stands for Lysergic acid diethylamide. LSD effects are similar to psilocybin mushrooms (magic mushrooms), as they both mimic the brain chemical serotonin. the duration of the trip lasts approximately 6 to 10 hours with the strongest effects occurring at 3 hours after ingestion. Pharmacology LSD tab dosing How to dose correctly What does LSD feel like? To safely ingest LSD it is crucial to understand that it is very potent even in low doses. A typical dose of LSD is 100 micrograms which is equivalent to 0.1 milligrams or roughly the size of a grain of sand. One tab can contain anywhere from 1 microgram to 500 micrograms. It is difficult to determine the correct dose of LSD because a couple grains of sand worth of LSD can turn a normal dose into an extremely strong one. Doses are sold in various forms including, blotter paper, gelatin tabs, or crystal LSD dissolved in alcohol known as a “vial.” It is not possible to precisely know how many micrograms are on a tab without lab testing so it is critical to take a test dose. Microdosing 1/20th to 1/10th of a tab no psychedelic (visual) effects but minor mood lifting may occur. The microdose level should only influence subconscious emotion, thinking, and perception. Many believe microdosing increases both productivity and creativity and has anti-depressent effects. The benefits are being researched but no definitive conclusions about risk and reward can be given without thorough research. Very low dose (1/10th to 1/5th of a tab Minor psychedelic (visual) effects may or may not occur. Colors may seem brighter and surfaces may have moving patterns covering them. Mood should be noticeably altered with increased deep thought and noticing details, colors, and surroundings like nature may be much different than sober perceptions. Low to moderate dose (1/4 to 1/5 of a tab) Effects will become very noticeable above a quarter tab. visual hallucinations like colors and patters will become apparent and increase in intensity as the dose increases after .25 tabs. Wonder filled thoughts and feelings of stimulation begin to intensify at this dose. Mood can increase with feelings of exitement and slight euphoria. Even a low dose can cause anxiety and sometimes fear if your mindset and location are not correct. Tripping in a very public place like a concert or crowded beach are more likely to cause anxiety compared to a calm house or soothing nature. normal dose (full psychedelic trip) 1 full tab 1 tab is designed to be the perfect dose for full psychedelic effects while usually remaining controllable and not too intense for. at 1 full tab the colors and patterns are very apparent and occur when eyes are both open and closed. Objects often “breath” which means swaying and bending in a magical type way. You may notice the floor, walls, trees, hands, and surfaces sway and have patterns overlayed on them. Vibrancy of colors is heightened and closed eye visuals contain all colors of the rainbow that create complex shapes and infinite kaleidoscopic patterns. Intense feelings of stimulation and alertness. Even though 1 tab is an average dose for a full trip there is still a chance that paranoia or anxiety can occur. The best way to prevent them is to take LSD with people you trust in a place that makes you calm / comfortable Very heavy dose (greater than 1 full tab) heavy doses above 1 full tab are very potent and marks the point where bad trips become more likely. The effects of 1.5 to 3 tabs may be much too intense for any beginner or even experienced people. At this dose the psychedelic visuals may distort and fill vision so intensely that it is difficult to see straight and identify things around you which is very dangerous. Thought loops are very common at these doses and negative loops including terror, paranoia, and detachment from reality may be overwhelming and cause outbursts or extreme confusion. It is critical to have someone you trust who remains sober to keep you safe on a dose that large. Ego death is possible when many tabs are taken at once. Ego death is when the trip is so strong you forget that you are alive and is similar to being in a trance. Time and reality and shattered and your actions and behavior may be out of your control. It is extremely risky to experience ego death alone, with strangers, or anywhere in public. To test the strength of a tab, it is advised to start by ingesting 10% of a tab to gauge the strength. 10% of a normal 100 microgram tab should not cause any visual distortions whatsoever. You may experience slight mood changes but such a low dose should cause very minimal noticeable effects. If visual effects are noticeable with 10% of a tab then the tab is much stronger than a standard dose. Once a low dose is tested you can help prevent taking too much in the future. If you are confident that 10% of a tab is not strong then slowly start increasing amount of dose up to a full tab. LSD can be absorbed in the mouth or digested in the stomach. The most effective method of ingestion involves placing the tab underneath the tongue then swallowing the paper 15 minutes later. Alternatively, the tab can be swallowed immediately but the psychedelic effects may be delayed a bit longer than the under the tongue method. After ingesting the tab, the effects should begin within 45 minutes. If there are no effects at all within 1.5 hours the tab is either very weak or did not contain LSD at all. DO NOT take another tab unless at least 2.5 hours have gone by with zero effects. You do not want to take another dose before the last one has gotten the full amount of time to onset. LSD Q&A Onset – occurs within an hour Intensity increase – hour 1 to 3 Peak - (strongest effects) – 3 hours after ingestion Come down - (effects slowly waring off) hour 4 to 8 "afterglow” - (lingering positive mood) – can last for 2 to 8 hours after effects have worn off How to see if your LSD is real It is critical to reagent test LSD. Please visit Dance Safe linked below and get drug testing kits. It may save your life. Click here to get reagents on Dance Safe Reagent testing LSD step 1 Ehrlich reagent Real LSD causes a purple color when it comes in contact with the Ehrlich reagent Any other color besides purple indicates the tab does not contain LSD and may be laced with a different drug It is critical to reagent test your LSD to confirm you have the correct drug. Reagent testing LSD is extremely recommended because it can save your life. The “Ehrlich” reagent test is the preferred test for LSD. The Ehrlich reagent kit will reliably test blotter tabs of LSD. The Ehrlich reagent works by placing one drop of the reagent on about 1/20th of a blotter tab. The reagent reacts with the chemical on the tab and changes colors based on the chemical reaction. If the LSD is real then the Ehrlich reagent will yield a purple color within 5 seconds to 5 minutes. If there is no color or anything different than purple you cannot be certain your tab contains LSD and you should throw the tabs away. Reagent testing LSD step 2 Hoffman reagent Real LSD causes a blue color when it comes in contact with the Hoffman reagent NBOMe drugs are an LSD imposter substance that can kill you. Make sure the color is not yellow or amber colored. Those colors indicate a drug different than LSD and may be NBOMe drugs. (See 25D and 25B NBOMe in the image to the right). You must use the Hoffman reagent as well to test tabs. Hoffman reagent can detect the difference between real LSD and different variants of NBOME. The Hoffman reagent yields a blue color when it touches real LSD and different types of yellow or pink for other substances like 25i-nbome, 2c-I, and 25B-NBOME. There are similarities and very important differences between LSD and NBOME. LSD dose ranges from 40 micrograms (low) to 250 (high) with the average being 100 to 150 micrograms. Whereas NBOME doses are mild at 250 to 450 micrograms high doses are around 450 to 800 micrograms. The dosages between LSD and NBOME seem different in numbers but the difference of 200 micrograms to 600 is extremely small to the naked eye. Since it is nearly impossible to visually distinguish how much of a drug is on blotter paper or in a vial or gelatin tabs it is best to test the substance with an Ehrlich reagent kit. LSD by itself can not kill you by overdose but NBOME can kill you very easily. The worst that can happen in a high LSD dose is terror, anxiety, and confusion. But you will live and not experience noticeable brain damage even in extremely high doses. On the other hand, NBOME compounds can directly kill you LSD in any form like blotter paper, gelatin tabs, or liquid in a vial is tasteless and odorless. An LSD dose cannot be visually measured because 100 micrograms is microscopic. It is essential to be aware that street dealers may sell dangerous counterfeit substances presented as LSD. For instance, the psychedelic compound 25I-NBOMe is sometimes passed off as acid. However, NBOMe compounds are much more harmful than LSD, only a few grains of salt worth of NBOME compounds can lead to severe health complications, including heart failure, seizures, and death. LSD doses typically range from 40 micrograms (low) to 250 micrograms (high), with the average dose falling between 100 to 150 micrograms. In contrast, NBOMe doses are considered mild at 250 to 450 micrograms, with high doses reaching around 450 to 800 micrograms. While the microgram gap may seem large, in reality, a difference of 300 micrograms is extremely hard to visually notice while being much more powerful. Given that visually determining the quantity of a substance on blotter paper, in a vial, or gelatin tabs is virtually impossible, it is highly recommended to test the substance using an Ehrlich reagent kit. NBOMe compounds have the potential to cause lethal consequences. The lethal dose of NBOMe can be as little as 2 milligrams (2000 micrograms), which is a minuscule amount. LSD Tolerance LSD often carries misconceptions and negative stigma in the public eye. While all psychoactive substances carry risks, the level and nature of the risk vary between different drugs. LSD is widely recognized as having a very low potential for addiction. The low addiction risk is due to the unique tolerance built for LSD when used consistently. When is LSD used more than once a week tolerance builds up quickly, requiring higher doses to achieve the same effects. For example, if someone takes a 100 microgram tab of LSD every day for a week, by the seventh day, that same 100 microgram tab would have significantly diminished psychedelic effects, perhaps feeling like only 1.5 micrograms which has zero psychedelic effects. The drastic drop in effect makes LSD nearly impossible to become addicted to because you have to increase the dose to absurd levels. After a week of everyday use, someone would have to consume 128 tabs to feel average psychedelic effects. The number of LSD needed to be consumed is doubled each consecutive day it is used which makes the likelihood of someone becoming addicted to LSD extremely low. Similarly, there have been zero reliably recorded cases of LSD overdose caused solely by LSD in those without prior medical conditions or mixing other substances with LSD. 100 LSD gel tabs Gel tabs come in many different colors and shapes Color or shape do not indicate strength or purity 100 LSD blotter tabs Blotter tabs can have infinite amount of designs. The design does not indicate strength or purity

Learn how amphetamines effect the brain from a simplified neuroscience perspective Meth and adderall pharmacology It might be suprising to some but meth and adderall work the EXACT SAME WAY in the brain everything written below applies to both meth and adderall equally main page American society often associates methamphetamine with addiction, death, overdose, and crazy people. Adderall is viewed as a medicine good for studying and productivity at work. Pharmacology research and chemical analysis shows that methamphetamine and Adderall are the EXACT SAME DRUG when it comes to addiction potential, psychoactive effects, as well as mental damage. All scientific literature you can find online will tell you the chemical structures are 99% similar and the 1% difference goes away one once the drug is ingested in any form. The images below displays the similarities. Amphetamine base chemical name is alpha-methylphenethylamine Crystal Methamphetamine is a hydrochloride salt Adderall is a mixture of levoamphetamine and dextroamphetamine Amphetamines bind to presynaptic membrane of dopaminergic neurons and release massive amounts of dopamine especially in the striatum. Then amphetamine molecules bind to dopamine reuptake transporters which prevents dopamine from leaving synaptic gap and reversing dopamine transporters which causes free dopamine to be transported out of the terminal. High doses of amphetamines even cause monoamine oxidase inhibition which prevents dopamine, epinephrine, norepinephrine, and serotonin breakdown. Inhibiting monoamine oxidase increases all monoamine prevalence and receptor interactions. Chemical comparison Amphetamine (Adderall) only has 1 more hydrogen and 1 less methyl group (CH3) than meth. Next page Our Clients

Learn about Amphetamines, the dose, purity, effects, and how they work in the brain How to safely use meth and adderall (amphetamines) Meth & adderall Q&A Drugs list Amphetamine pharmacology Amphetamines are a group of stimulant drugs including Meth and Adderall. There are thousands of drugs in the amphetamine class but these 2 are the most prevalent in society. Methamphetamine and amphetamine salt (Adderall) yield extremely similar effects and carry similar risks when consumed in recreational doses. Note that any information written about ADDERALL refers to those who abuse and get high on it. Prescribed amounts for those who need the drug are not included in this article. People with ADHD taking prescribed 5mg to 20mg of Adderall are not the same as an average person snorting (sniffing) many crushed up pills to get high. Methamphetamine is also known as meth, crank, ice, crystal. Adderall is sometimes called a smart drug or study drug. Methamphetamine is illegal in all circumstances whereas Adderall can be legally prescribed for the treatment of disorders like attention deficit hyperactivity disorder (ADHD). Both drugs are central nervous stimulants or “uppers” that induce euphoria, explosive amount of energy, increase enthusiasm, ramp up heart rate, and constrict pupils / circulation. High doses of these drugs lessen the desire for eating or sleeping which has many mental and bodily consequences. The Amphetamine class of drugs used recreationally cause the user to feel stronger, more confident, smarter, and more aware then they really are. how illegal is meth / adderall meth & adderall myths The general population views meth as a hard drug that is highly addictive and ruins the life of everyone who uses it. Someone imagining a meth addict visualizes a bone skinny, raggedy, toothless, dirty homeless person. Meanwhile, when someone visualizes an Adderall user they often visualize a businessman taking drugs to manage their busy work or busy family schedule. Put simply, meth is viewed as a dangerous drug that ruins lives and Adderall as a drug used for studying and productivity for normal people. The truth, according to pharmacology, is that pure meth and Adderall are just as addictive and relatively the same danger level to consume when taken at the same dose. Both meth and Adderall equally cause sleep deprivation, weight loss, dopamine deficiency, and brain alterations. Both chemicals function the same way in the brain and carry extremely similar overdose potential. Society is mislead because meth is illegal and Adderall is a “medicine” so it is reasonable to believe that a medicine is good for you and illegal drugs are dangerous. Sadly, this is not the case. Adderall (dextro and levoamphetamine) is not a better or worse choice to make legal than using medical grade methamphetamine. The one and only reason Adderall may be considered a better option to use recreationally is because pills from a pharmacy are not likely to be laced, have impurities, and have accurate dosing. Theoretically, if you have 2 pills, one contains meth and the other contains Adderall amphetamines. Assume both are medical grade and contain no harmful additives. It would be impossible to tell which pill contains what based solely off of the effects of the drug. The only way to tell is if you test the pill with a reagent testing kit. Overall, it is highly recommended to learn about drugs on your own and not believe that legal medicines are always good and illegal drugs will always kill you. Adderall and meth are effectively the same drug with totally different public perceptions. Methamphetamine and Adderall are both Schedule 2 drugs in the United States. Schedule 2 drugs are considered to have high potential for abuse potentially leading to severe psychological or physical dependence. The scheduling of a drug is determined by the Drug Enforcement Administration (DEA) in America. Other Schedule 2 drugs include cocaine, Ritalin, oxycodone, and fentanyl. The scheduling of drugs in America is very controversial and the ranking does not always align with the current scientific research regarding the danger and abuse potential of the substances. Adderall dosing Instant release Tablets made of pressed powder effects last 4 to 6 hours usually lower dosages (5mg to 15mg) but sometimes higher dosages (30mg) Extended release capsules capsule full of amphetamine beads effects typically last 8 to 12 hours, possibly longer Higher dosages (20mg to 30mg) Adderall is available as either colored, stamped pills or orange capsules with beads. Pills provide immediate effects within an hour, while capsules offer extended release over 6urs. Some abuse Adderall by crushing snorting it, seeking a quicker rush of euphoria, which is dangerous. Snorting can harm the nose and respiratory system, as the fillers are not meant for inhalation, and it increases the drug's addictive potential due to the rapid onset of effects. Meth dosing Methamphetamine is often found in powder or crystalized form. Powder meth is often snorted, injected, swallowed in capsules. Whereas crystal meth is not snorted because it severely cuts and tears the inside of the nose. Crystal can be smoked, melted then injected, or swallowed. Due to meth being illegal and not created by a regulated company the ingredients in meth are unknown. It is recommended to swallow meth opposed to snorting, smoking, and definitely avoid injecting. Making meth includes using extremely toxic chemicals like strong acids, phosphorous and many dangerous chemicals that can damage your nose, lungs, and veins. It is extremely recommended to never do meth in any form but if you do meth it Is extremely recommended that swallowing an ACCURATELY WEIGHED small dose is the best way to avoid excess damage to internal organs. Administering meth in other ways than swallowing can lead to damage to nasal cavities, lungs, teeth, throat, and veins. The phrase “meth mouth” exists because people who smoke meth for a long time have severe tooth and gum damage. The actual methamphetamine drug itself does not cause mouth damage. It is the toxic additives that are leftover from creating the drug. How to remain safe using street Adderall Street Adderall are very commonly counterfeited, laced with meth or other drugs, and can contain the wrong dose. These risks apply to Adderall pills not from a pharmacy / prescription. The rule of thumb is if you did not personally pick them up from the pharmacy with your prescription then you MUST assume they are counterfeit. Never believe a dealer that say they got them from a pharmacy even if they show you a prescription. Always assume a dealers drugs will be laced . Dealers and producers can buy amphetamine powder and a pill press machine from amazon to make pills that looks identical to a real pharmaceutical grade pill. Do not try to visually distinguish real from fake pills. Additionally, if you test your Adderall and it tests positive for the correct drug, you can never know how much of the drug is in the pill. Never blindly believe the pills label If its stamped “30” or “15” indicating the amount of milligrams. Counterfeit dealers often press an incorrect amount of the amphetamine powder into the pill. There is not a test to determine how strong the pill is so after reagent testing the pill , it is recommended to swallow 10% of the pill to gauge how strong it is. Counterfeit Adderall often contain no Adderall at all. Many pills are made with powdered methamphetamine mixed with colored pill binder and pressed into the shape and color of real pills. Dealers can make more money selling meth and calling it Adderall. If you get Adderall pills from anywhere besides a pharmacy with your prescription you MUST reagent test the drug to make sure your pills are not methamphetamine. Many websites sell the test kits can decipher Adderall from meth It is critical to reagent test meth / Adderall. Please visit Dance Safe linked below and get drug testing kits. It may save your life. Click here to get reagents on Dance Safe How to see if your Adderall is real Step 1 Buy the marquis OR Liebermann reagent. Either of these tests will turn orange when EITHER meth or Adderall is detected. The marquis / Liebermann test will tell you if you have a type of amphetamine and not a completely different drug like heroin or MDMA. Only Meth and Adderall turn orange when using this test. Step 2 Buy the Simon’s reagent to see if you have meth OR Adderall. When placing a drop of the simons reagent on a small portion of the pill, the reagent will turn blue if the pill is made of meth and have no reaction if the pill is Adderall. step 3 You must use a fentanyl contamination test. As little as 2 grains of sand worth of fentanyl can be deadly. This step is as important as the previous 2 steps. Information to note YOU MUST UNDERSTAND that both marquis OR lieberman in addition to simons need to be used. Using only 1 reagent and not the other will not give you enough information to confidently say the pill is meth or Adderall. After both steps of reagent testing it is likely that the results from the reagents determined the correct drug.

Marquis Reagent 101: The ultimate guide to MDMA, Meth, and Opiate testing With the rise of designer drugs and research chemicals in social settings, it is crucial for users to know exactly what substances they... Ehrlich Reagent 101: The Ultimate Guide to the LSD test kit Learn how the Ehrlich reagent test kit identifies psychedelic drugs

Learn about the creator of DrugSpeak. Why does drugspeak.org exist and what is it. Author information Mission & Goals My name is Kevin and I am the sole creator of Drugspeak.org. I am currently pursuing my bachelors in behavioral neuroscience at Florida State University. I believe there is a lack of easily accessible information on true unbiased science behind drugs on the internet. Drug Speak delivers reputable and up-to-date information on current drug research. My aim is to distribute information without political or economic bias to provide the researched-based understanding of drugs. Become a DrugSpeak Member X (Twitter) Follow me! @DrugSpeak_org Enter your email here Sign Up Thanks for submitting!

Learn about dosing, purity, and effects of cocaine. General Cocaine info Cocaine also known as coke, blow, and snow, is a stimulant powder that is inhaled through the nose (aka snorting). Cocaine has 2 common forms: powder that is snorted, and the crystal rock version called crack that is smoked. Both cocaine and crack contain the same psychoactive chemical. Snorted cocaine increases heart rate, blood pressure, and boosts general energy. Within a couple minutes of ingestion, the user feels a rush of euphoria and energy kick that feels very sharp and pleasurable. Many users often feel like they are stronger than they are, more confident, and more energetic. Users often speak quicker and move their body more via fidgeting or dancing if in a party or bar setting. Cocaine has a similar feeling to Adderall but much less duration and cocaine’s effects are felt much quicker than an Adderall pill. Cocaine Q&A pharmacology Cocaine is extracted from these leaves called Coca leaves It is critical to reagent test MDMA. Please visit Dance Safe linked below and get drug testing kits. It may save your life. Click here to get reagents on Dance Safe cocaine vs crack How to dose cocaine How illegal is cocaine? Americans often view cocaine as a “high class” drug because of its high cost and history related to celebrities and wealthy people who use it. Many people believe that cocaine is a rich people’s party drug but crack is a drug that brings images of homelessness, addiction, hopelessness. This societal view is very dangerous as it downplays the dangers of cocaine use. It must be understood that powder cocaine and crack provide the exact same high and carry the same general dangers. The only difference between the two is that crack is smoked therefore the high feels more like a “rush” and effects are felt very quickly within 20 seconds. Cocaine Is snorted so the effects take a couple minutes to be felt which decreases the sense of quick euphoria. It is true that the rushing euphoria of crack is more psychologically addictive but both cocaine and crack have the exact same overall high. After all, crack is just powdered cocaine cooked together with baking soda to turn it into a crystal. American society has an inaccurate perception that cocaine is more socially acceptable than crack. Cocaine is an illegal Schedule 2 drug in the United States. Schedule 2 drugs are considered to have high potential for abuse with use potentially leading to severe psychological or physical dependence. The scheduling of a drug is determined by the Drug Enforcement Administration (DEA) in America. Other Schedule 2 drugs include Adderall, methamphetamine, and oxycodone, and fentanyl. The scheduling of drugs in America is very controversial and the ranking does not always align with the current scientific research regarding the danger and abuse potential of the substances. A dose of cocaine is often described one of two ways: bumps and lines. A “bump” is a smaller dose than a line where someone uses a tool like a key to pick up a little pile of powder and snorts it. The other way is a line where a larger dose of cocaine is placed on a surface like a table and snorted along the length of the line. The weight of a bump or line cannot be recommended because the purity of different people’s cocaine will be different. A 10 milligram bump of 100% pure cocaine is 4 times as strong as 25% pure coke so there really is no average size dose of cocaine. As a rough guide, always assume your cocaine is really strong so you do not underestimate it and take too much. Both powder cocaine and crack cocaine are very hard to dose correctly. Many factors such as purity, other adulterants (laced) or inaccuracies in weighing all make a recommendation for dosing extremely difficult. Since Cocaine is just a generic looking white powder it is nearly impossible to understand what the powder is made of by taste or smell alone. It is always urgently recommended to reagent drug test your substances before use. In America, Cocaine is heavily adulterated and cut with chemicals to thin it out or laced with other drugs to enhance the effects. Inactive ingredients like baking soda, baby powder, creatine, or lidocaine/ procaine, or a number of others are almost always added before a customer receives it. While active ingredients are less frequent it is adds risk and harm potential, cocaine is sometimes cut with caffeine, meth, and even opioids like heroin or fentanyl. Since all the inactive and active ingredients listed above could be generic white powders you can never be sure what is in cocaine. Pure cocaine and lethal dose fentanyl laced powder look the exact same. Furthermore, when adulterants are mixed with cocaine, most cutting agents are odorless so both look and smell are not able to be noticed. Fentanyl, caffeine, meth, are odorless when mixed with cocaine so a white powder called cocaine can really be made of anything. Cocaine is produced majorly in south America then trafficked to everywhere else in the world. Countries like Colombia, Bolivia, and Peru all have a monopoly on the cocaine production market. Cartels within those countries account for nearly 100% of the cocaine produced and distributed around the world. Although, cocaine in those countries is produced pure without adulterants, once that pure powder gets trafficked to another country the drug is cut and altered each time it changes hands. While America and Europe are both different distances from South America, the cutting agents used are largely the same. These substances include acetaminophen, phenacetine, caffeine, lidocaine and in almost 70% of the samples levamisole (363 out of 524 samples) dangers of Mixing cocaine and alcohol Cocaine is often a party drug used at clubs, festivals, and parties. Partiers that drink alcohol often use cocaine at the same time to diminish the sedative effects of alcohol and make them more alert. Mixing cocaine with alcohol is dangerous for many reasons. Firstly, alcohol is a depressant and cocaine is a stimulant so mixing them can make the user feel more sober than they actually are. Cocaine use while drinking can make someone feel as if they can drink more without getting sick or “blacking out.” This makes alcohol poisoning and injury from falling much more likely. Secondly, mixing cocaine and alcohol creates a very unique chemical reaction in the body. Mixing these drugs creates the psychoactive chemical cocaethylene in the body. Cocaethylene causes the euphoric effects of cocaine to increase and create severe toxicity in the cardiovascular system. Since alcohol is a depressant it causes the cardiovascular system to relax and dilates blood vessels including the vessels in the nose. Dilated nose blood vessels means that more of the cocaine snorted will reach the blood stream and heighten the drug effects even more. Cocaethylene is extremely toxic and more damaging than either cocaine or alcohol by themselves. The damage caused by alcohol plus cocaine plus cocaethylene makes this drug combination one of the most dangerous and toxic there is. cocaine main page toxicity and overdose potential of cocaine Cocaine overdose is quite common for a multitude of reasons. Coke is a strong nervous system stimulant which ramps up heart rate, metabolism, temperature, and blood pressure. If too much cocaine is consumed the spike in bodily functions may cause overexertion of organs causing heart attack, overheating (heat stroke), lung problems like pneumonia, and sleep deprivation in chronic users. Seizures are also possible due to cocaines stimulating effects in the brain. Cocaine outside of production countries such as Bolivia and Colombia is often cut with various things to mimic the effects of cocaine or thin the drug out. Everything from baby powder to lidocaine to fentanyl can be mixed into cocaine powder because all those substances are white powders visually identical to the pure drug. As with every other drug, it is heavily recommended to reagent test the substance to identify the chemicals and drugs it is made of. Reagent testing kits are fairly inexpensive yet they can save your life and spare your from ingesting a drug laced with something deadly like fentanyl. The Marquis and Liebermann reagent tests are recommended for cocaine testing. The marquis reagent can identify cocaine mixed with amphetamines Morris, Marquis, and Liebermann reagents. These kits that are capable of detecting specific cuts (levamisole and lidocaine) It is critical to reagent test Cocaine. Please visit Dance Safe linked below and get drug testing kits. It may save your life. Click here to get reagents on Dance Safe How to reagent test Cocaine Reagent testing cocaine step 1 Morris reagent Real cocaine causes a blue color when it comes in contact with the morris reagent Any other color besides blue indicates the powder may be laced with another drug. Morris reagent is a 2 step process with 2 liquids used at the same time on the same sample. Reagent testing cocaine step 2 Marquis reagent This reagent does not confirm the sample is cocaine. It is meant to show you possible drugs laced into the powder. The marquis reagent must be used with step 1 and 3 to be confident. Reagent testing cocaine step 3 Liebermann reagent Real cocaine causes a yellow tan color Note that ketamine also has the same color. The Morris reagent (step 1) can distinguish ketamine from cocaine. Final Step ALWAYS USE A FENTANYL TESTING STRIP Use a fentanyl test for every drug you intend to take. it will save your life.

Learn all about the psychedelic drug ayahuasca containing DMT. How to use it, how to stay safe, and how it works in the brain and body. Ayahuasca DMT home page Ayahuasca is a brewed liquid traditionally from root bark and plants that contain DMT. Ayahuasca has a long history of use by South American religious groups as a sacred ritual where ayahuasca (DMT) drinks are consumed to cause psychedelic and spiritual experiences. The word ayahuasca is the name of a vine from the Amazon that contains DMT. While there are many plants used for ayahuasca a popular source of DMT is from the root bark of the plant Mimosa Hostilis. Mimosa Hostilis root bark is boiled which extracts the DMT from it. Drinking DMT root bark tea by itself will not give psychedelic effects. DMT is not an orally active molecule which is why the powder is often smoked. To make DMT tea orally active there must be a Monoamine oxidase inhibitor (MAOI) present. The liver enzyme Monoamine Oxidase breaks the DMT molecule down into a non-psychoactive derivative before it has a chance to cause psychedelic effects. Many metabolites are produced from DMT break down but mainly DMT-N-oxide (DMT-NO), and indole-3-acetic acid (IAA) which are not hallucinogenic. To prevent DMT breakdown in the liver the monoamine oxidase (MAO) must be blocked by way of a monoamine oxidase inhibitor (MAOI). Many ayahuasca brews contain both a bark like Mimosa Hostilis and a plant containing MAOIs such as Banisteriopsis caapi (BC) and Peganum harmala (PH). Both MAOI plants contain an active monoamine oxidase inhibitor such as β-carbolines harmalol, harmine, and harmaline. By brewing a DMT-containing bark like Mimosa Hostilis and MAOI-containing plant such as Peganum harmala together the resulting brew will cause hallucinogenic DMT effects when consumed. DMT containing plants such as Mimosa hostilis root bark are usually legal to purchase and possess in the united states. Although pure DMT powder is a schedule 1 illegal drug there is a grey area in the law about the entire plant. Purchasing and possessing the plant or bark is legal while extracting and consuming DMT is illegal. Mimosa hostilis root bark (contains DMT) Banisteriopsis caapi vine (contains MAOI inhibitor) Finished product: ayahuasca brew (contains DMT and MOAI inhibitor)

Learn how MDMA / ecstasy effect the brain from a simplified neuroscience perspective. MDMA Pharmacology MDMA Home page MDMA standing for Methylene-dioxy-methyl-amphetamine acts both as a psychedelic and stimulant in the catecholaminergic psychedelic class also known as phenylethylamine psychedelics and amphetamine stimulants. MDMA works by increasing synaptic concentration of serotonin, norepinephrine, and to a lesser extent, dopamine. When the MDMA molecule crosses the blood brain barrier the chemical is shaped similar enough to serotonin to enter a serotonin transporter. Then the MDMA molecules inhibit the vesicular monoamine transporters (VMAT) which causes serotonin to be rapidly released from the vesicles housing it and accumulates in the cytosol. Finally, MDMA changes the direction of serotonin transporters to release excessive amounts of serotonin out of the neuron which floods into the synaptic cleft. Serotonin reuptake is inhibited and leaves massive amounts of serotonin in the synaptic cleft to stimulate serotonin receptors continuously causing them to fire. MDMA mechanism in the brain

< Back Understanding the Marquis Drug Reagent The Marquis drug reagent is a simple yet powerful chemical test used to identify certain substances in drugs. It has gained popularity among harm reduction advocates and recreational drug users alike as a means of ensuring safety before consumption. In this article, we will explore what the Marquis reagent is, how it works, what substances it can identify, and why it is essential to use it before taking drugs. What is the Marquis Drug Reagent? The Marquis reagent is a color-changing chemical solution primarily composed of formaldehyde and concentrated sulfuric acid. When mixed with a sample of a substance, it reacts chemically, producing distinct color changes that can indicate the presence of various drugs. This reagent is particularly useful in the context of illicit drug use, where the purity and identity of substances can be uncertain. How Does the Marquis Reagent Work? The Marquis reagent operates on the principle of chemical reactions between the reagent and certain compounds found in drugs. When a sample is introduced to the reagent, it undergoes a series of reactions that produce specific colors. Each color corresponds to different substances, allowing users to infer what they might be consuming. Here’s a basic overview of the process: Sample Preparation: A small amount of the substance to be tested is placed on a clean surface or in a test tube. Adding the Reagent: A few drops of the Marquis reagent are added to the sample. Observation: The mixture is observed for color changes, which are compared against a color chart that indicates the presence of specific drugs. What Substances Does the Marquis Reagent Identify? The Marquis reagent is particularly effective in identifying a range of substances. Why Should People Use the Marquis Reagent Before Consuming Drugs? Increased Safety: The reagent helps users identify potentially dangerous substances or adulterants that could lead to overdose or serious health risks. Reducing Uncertainty: The illicit drug market is often unpredictable, and the Marquis reagent can provide a level of assurance about the identity of a substance. Promoting Responsibility: Using the reagent encourages a culture of responsibility among drug users, fostering awareness and caution. Final tips While the marquis reagent is not a foolproof method, using it can significantly reduce the risks associated with drug consumption. Always prioritize safety and use multiple reagents in addition to a fentanyl testing strip before consuming any substance. Psychedelic Testing instructions 1 Ehrlich reagent Many common psychedelics elicit a purple color when it comes in contact with the Ehrlich reagent. Any other color besides purple indicates the tab does not contain LSD and may be laced with a different drug 2 Hoffman reagent For testing LSD use Hoffman which causes a blue color when it comes in contact with the Hoffman reagent NBOMe drugs are an LSD imposter substance that can kill you. Make sure the color is not yellow or amber colored. Those colors indicate a drug different than LSD and may be NBOMe drugs. Read about Hoffman 3 Fentanyl test strip Any drug can be laced with fentanyl and kill you. Always use a test strip on every drug.

< Back Identifying Common Psychedelics with the Ehrlich Test Kit The Ehrlich test kit helps determine if a substance is a common psychedelic. It can detect LSD, psilocybin (magic mushrooms), DMT, Mescaline, ETH-LAD, and AL-LAD (LSD analogs). Many psychedelics react with the Ehrlich reagent, resulting in a light to deep purple color. If no color or a color other than purple appears, the substance is not a classical psychedelic. This drug test kit functions by reacting with a part of a molecule known as an "indole ring." Classic psychedelics like LSD, DMT, Mescaline, and others cause hallucinogenic effects because they mimic the brain chemical serotonin, which contains an indole ring in its molecular structure. Testing a substance with the Ehrlich reagent can indicate the presence of an indole ring. This reagent cannot specify which psychedelic is present, but it can confirm the presence of a psychedelic. For instance, a sample of fentanyl will not react with the Ehrlich reagent. Therefore, if a tab of LSD shows no reaction with the test kit, it indicates that there is no LSD on the tab, and it should be discarded. Once you confirm the presence of a psychedelic, other reagents can be used to narrow down the possibilities. Using multiple reagents can provide a clearer idea of which drug you have. Finally, always use a fentanyl testing strip alongside other reagents. Psychedelic Testing instructions 1 Ehrlich reagent Many common psychedelics elicit a purple color when it comes in contact with the Ehrlich reagent. Any other color besides purple indicates the tab does not contain LSD and may be laced with a different drug 2 Hoffman reagent For testing LSD use Hoffman which causes a blue color when it comes in contact with the Hoffman reagent NBOMe drugs are an LSD imposter substance that can kill you. Make sure the color is not yellow or amber colored. Those colors indicate a drug different than LSD and may be NBOMe drugs. Read about Hoffman 3 Fentanyl test strip Any drug can be laced with fentanyl and kill you. Always use a test strip on every drug.